corticotrophin-releasing hormone [Ligand Id: 912] activity data from GtoPdb

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  • CRF1 receptor in Human [GtoPdb: 212] [UniProtKB: P34998]
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  • CRF2 receptor in Human [GtoPdb: 213] [UniProtKB: Q13324]
  • CRF2 receptor in Mouse [GtoPdb: 213] [UniProtKB: Q60748]
  • CRF2 receptor in Rat [GtoPdb: 213] [UniProtKB: P47866]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CRF1 receptor in Human [GtoPdb: 212] [UniProtKB: P34998]
GtoPdb - - 9 pKd - - - Proc Natl Acad Sci USA (1993) 90: 8967-71 [PMID:7692441];
J Neurochem (1997) 69: 1640-9 [PMID:9326293];
Eur J Biochem (1998) 258: 78-84 [PMID:9851694];
J Pharmacol Exp Ther (2001) 296: 113-20 [PMID:11123370];
Endocrinology (1996) 137: 2167-70 [PMID:8612563];
Nature (1995) 378: 287-92 [PMID:7477349]
CRF2 receptor in Human [GtoPdb: 213] [UniProtKB: Q13324]
GtoPdb - - 7.4 pKd - - - J Pharmacol Exp Ther (2001) 296: 113-20 [PMID:11123370]
CRF2 receptor in Mouse [GtoPdb: 213] [UniProtKB: Q60748]
GtoPdb - - 7.8 pKi - - - Endocrinology (1996) 137: 2167-70 [PMID:8612563];
Nature (1995) 378: 287-92 [PMID:7477349]
CRF2 receptor in Rat [GtoPdb: 213] [UniProtKB: P47866]
GtoPdb - - 7.9 pKd - - - Endocrinology (1996) 137: 2167-70 [PMID:8612563]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.