netarsudil [Ligand Id: 9322] activity data from GtoPdb

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  • Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
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  • Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
GtoPdb - - 7.49 pIC50 32.6 nM IC50 Eur J Med Chem (2019) 180: 449-456 [PMID:31330446]
Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
GtoPdb - - 8.7 pKi 2 nM Ki Bioorg Med Chem Lett (2016) 26: 2475-80 [PMID:27072905]
GtoPdb - - 7.95 pIC50 11.2 nM IC50 Eur J Med Chem (2019) 180: 449-456 [PMID:31330446]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.