RWJ-56423 [Ligand Id: 9333] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL256892 (RWJ-56423) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| serine protease 1/Trypsin I in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL209] [GtoPdb: 2397] [UniProtKB: P07477] | ||||||||
| ChEMBL | Binding affinity against human alpha trypsin | B | 8.09 | pKi | 8.1 | nM | Ki | J Med Chem (2004) 47: 769-787 [PMID:14761180] |
| serine protease 1 in Bovine [GtoPdb: 2397] | ||||||||
| GtoPdb | - | - | 8.09 | pKi | 8.09 | nM | Ki | J Med Chem (2003) 46: 3865-76 [PMID:12930148] |
| tryptase alpha/beta 1 in Human [GtoPdb: 2424] [UniProtKB: Q15661] | ||||||||
| GtoPdb | - | - | 8 | pKi | 10 | nM | Ki | J Med Chem (2003) 46: 3865-76 [PMID:12930148] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
