PF-06263276 [Ligand Id: 9432] activity data from GtoPdb

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  • Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458]
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  • Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
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  • Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
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  • tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Janus kinase 1 in Human [GtoPdb: 2047] [UniProtKB: P23458]
GtoPdb - - 8.66 pIC50 2.2 nM IC50 J. Med. Chem. (2017) 60: 767-786 [PMID:27983835]
Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
GtoPdb - - 7.64 pIC50 23.1 nM IC50 J. Med. Chem. (2017) 60: 767-786 [PMID:27983835]
Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
GtoPdb - - 7.22 pIC50 59.9 nM IC50 J. Med. Chem. (2017) 60: 767-786 [PMID:27983835]
tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
GtoPdb - - 7.53 pIC50 29.7 nM IC50 J. Med. Chem. (2017) 60: 767-786 [PMID:27983835]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.