compound 43 [PMID: 26751273] [Ligand Id: 9492] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| S1P1 receptor in Human [GtoPdb: 275] [UniProtKB: P21453] | ||||||||
| GtoPdb | In β-arrestin and receptor internalisation assays. | - | 8.8 | pEC50 | - | - | - | J Med Chem (2016) 59: 1003-20 [PMID:26751273] |
| S1P2 receptor in Human [GtoPdb: 276] [UniProtKB: O95136] | ||||||||
| GtoPdb | In a S1P2R yeast reporter assay. | - | 4.5 | pEC50 | <31628 | nM | EC50 | J Med Chem (2016) 59: 1003-20 [PMID:26751273] |
| S1P3 receptor in Human [GtoPdb: 277] [UniProtKB: Q99500] | ||||||||
| GtoPdb | In a GTPγS assay. | - | 5.1 | pEC50 | 7943 | nM | EC50 | J Med Chem (2016) 59: 1003-20 [PMID:26751273] |
| S1P4 receptor in Human [GtoPdb: 278] [UniProtKB: O95977] | ||||||||
| GtoPdb | In an aequorin calcium accumulation assay. | - | 4.4 | pEC50 | <39810 | nM | EC50 | J Med Chem (2016) 59: 1003-20 [PMID:26751273] |
| S1P5 receptor in Human [GtoPdb: 279] [UniProtKB: Q9H228] | ||||||||
| GtoPdb | In an aequorin calcium accumulation assay. | - | 7.78 | pEC50 | 16.6 | nM | EC50 | J Med Chem (2016) 59: 1003-20 [PMID:26751273] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
