A-971432 [Ligand Id: 9496] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| S1P1 receptor in Human [GtoPdb: 275] [UniProtKB: P21453] | ||||||||
| GtoPdb | - | - | 6.44 | pIC50 | 362 | nM | IC50 | J Med Chem (2015) 58: 9154-70 [PMID:26509640] |
| S1P5 receptor in Human [GtoPdb: 279] [UniProtKB: Q9H228] | ||||||||
| GtoPdb | In a GTPγS assay using membranes from S1P5-transfected HEK293 cells. | - | 8.24 | pEC50 | 5.7 | nM | EC50 |
J Med Chem (2015) 58: 9154-70 [PMID:26509640]; Hum Mol Genet (2018) 27: 2490-2501 [PMID:29688337] |
| GtoPdb | In a forskolin-induced cAMP inhibition assay in S1P5-transfected CHO cells. | - | 8.39 | pEC50 | 4.1 | nM | EC50 | J Med Chem (2015) 58: 9154-70 [PMID:26509640] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
