glycyl-sarcosine [Ligand Id: 9505] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL175737 (Glycylsarcosine, Gly-Sar, Gly-Sarcosin) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Peptide transporter 2/Solute carrier family 15 member 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743125] [GtoPdb: 985] [UniProtKB: Q16348] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of Cephalexin uptake in SKPT cells | F | 4.19 | pKi | 64000 | nM | Ki | J Biol Chem (1995) 270: 25672-25677 [PMID:7592745] |
| ChEMBL | Substrate uptake by the Peptide Transporter 2 (PEPT2, SLC15A2) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC15A2 cells (PubChem AID: 1794819) | F | 4.41 | pEC50 | 39000 | nM | EC50 | Membrane potential based assay for SLC15A2 using HEK-293 SLC15A2 OE cells |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
