ChEMBL ligand: CHEMBL12318 (Acide clodronique, Acido clodronico, Clodronate, Clodronic acid)
Type IV secretion-like conjugative transfer relaxase protein TraI in Escherichia coli (strain SMS-3-5 / SECEC) [ChEMBL: CHEMBL4296318] [UniProtKB: B1LRJ1] There should be some charts here, you may need to enable JavaScript!
Vesicular nucleotide transporter in Human [GtoPdb: 1010] [UniProtKB: Q9BYT1] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Type IV secretion-like conjugative transfer relaxase protein TraI in Escherichia coli (strain SMS-3-5 / SECEC) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4296318] [UniProtKB: B1LRJ1]
ChEMBL	Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assay	B	8.52	pKi	3	nM	Ki	Proc Natl Acad Sci U S A (2007) 104: 12282-12287 [PMID:17630285]
Vesicular nucleotide transporter in Human [GtoPdb: 1010] [UniProtKB: Q9BYT1]
GtoPdb	Using a quantitative transport assay system involving proteoliposomes containing only expressed and purified protein.	-	7.81	pIC50	15.6	nM	IC50	Proc Natl Acad Sci USA (2017) 114: E6297-E6305 [PMID:28720702]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]