Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL12318 (Clodronic acid) |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
Type IV secretion-like conjugative transfer relaxase protein TraI in Escherichia coli (strain SMS-3-5 / SECEC) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4296318] [UniProtKB: B1LRJ1] | ||||||||
ChEMBL | Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assay | B | 8.52 | pKi | 3 | nM | Ki | Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 12282-12287 [PMID:17630285] |
Vesicular nucleotide transporter in Human [GtoPdb: 1010] [UniProtKB: Q9BYT1] | ||||||||
GtoPdb | Using a quantitative transport assay system involving proteoliposomes containing only expressed and purified protein. | - | 7.81 | pIC50 | 15.6 | nM | IC50 | Proc Natl Acad Sci USA (2017) 114: E6297-E6305 [PMID:28720702] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]