H4 antagonist 48 [Ligand Id: 9879] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| H4 receptor in Human [GtoPdb: 265] [UniProtKB: Q9H3N8] | ||||||||
| GtoPdb | Radioligand competitive binding assay using [3H]Histamine as tracer, and membrane preparations from CHO-K1 cells expressing human H4 receptor. | - | 7.57 | pIC50 | 27 | nM | IC50 | J Med Chem (2018) 61: 2949-2961 [PMID:29579390] |
| H4 receptor in Mouse [GtoPdb: 265] [UniProtKB: Q91ZY2] | ||||||||
| GtoPdb | Radioligand competitive binding assay using [3H]Histamine as tracer, and membrane preparations from CHO-K1 cells expressing mouse H4 receptor. | - | 6.54 | pIC50 | 290 | nM | IC50 | J Med Chem (2018) 61: 2949-2961 [PMID:29579390] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
