cortistatin A [Ligand Id: 9885] activity data from GtoPdb

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  • Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 Rho associated coiled-coil containing protein kinase 1 Human
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  • Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 Rho associated coiled-coil containing protein kinase 2 Human
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  • cyclin dependent kinase 19 in Human [GtoPdb: 1972] [UniProtKB: Q9BWU1]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 cyclin dependent kinase 19 Human
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  • cyclin dependent kinase 8 in Human [GtoPdb: 1980] [UniProtKB: P49336]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 cyclin dependent kinase 8 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
GtoPdb - - 6.6 pKd 250 nM Kd Angew Chem Int Ed Engl (2009) 48: 8952-7 [PMID:19844931]
Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
GtoPdb - - 6.66 pKd 220 nM Kd Angew Chem Int Ed Engl (2009) 48: 8952-7 [PMID:19844931]
cyclin dependent kinase 19 in Human [GtoPdb: 1972] [UniProtKB: Q9BWU1]
GtoPdb - - 8 pKd 10 nM Kd Angew Chem Int Ed Engl (2009) 48: 8952-7 [PMID:19844931]
cyclin dependent kinase 8 in Human [GtoPdb: 1980] [UniProtKB: P49336]
GtoPdb - - 7.77 pKd 17 nM Kd Angew Chem Int Ed Engl (2009) 48: 8952-7 [PMID:19844931]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.