NIK SMI1 [Ligand Id: 9964] activity data from GtoPdb

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  • protein kinase D1 in Human [GtoPdb: 1489] [UniProtKB: Q15139]
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  • leucine rich repeat kinase 2 in Human [GtoPdb: 2059] [UniProtKB: Q5S007]
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  • mitogen-activated protein kinase kinase kinase 14 in Human [GtoPdb: 2074] [UniProtKB: Q99558]
  • mitogen-activated protein kinase kinase kinase 14 in Mouse [GtoPdb: 2074] [UniProtKB: Q9WUL6]
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  • mitogen-activated protein kinase kinase kinase kinase 5 in Human [GtoPdb: 2089] [UniProtKB: Q9Y4K4]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
protein kinase D1 in Human [GtoPdb: 1489] [UniProtKB: Q15139]
GtoPdb - - 7.12 pKi 75.2 nM Ki Nat Commun (2018) 9: 179 [PMID:29330524]
leucine rich repeat kinase 2 in Human [GtoPdb: 2059] [UniProtKB: Q5S007]
GtoPdb - - 6.61 pKi 247.8 nM Ki Nat Commun (2018) 9: 179 [PMID:29330524]
mitogen-activated protein kinase kinase kinase 14 in Human [GtoPdb: 2074] [UniProtKB: Q99558]
GtoPdb - - 9.64 pKi 0.23 nM Ki Nat Commun (2018) 9: 179 [PMID:29330524]
mitogen-activated protein kinase kinase kinase 14 in Mouse [GtoPdb: 2074] [UniProtKB: Q9WUL6]
GtoPdb - - 9.4 pKi 0.4 nM Ki Nat Commun (2018) 9: 179 [PMID:29330524]
mitogen-activated protein kinase kinase kinase kinase 5 in Human [GtoPdb: 2089] [UniProtKB: Q9Y4K4]
GtoPdb - - 7.3 pKi 49.6 nM Ki Nat Commun (2018) 9: 179 [PMID:29330524]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.