SH045 [Ligand Id: 9968] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • TRPC3 in Human [GtoPdb: 488] [UniProtKB: Q13507]
There should be some charts here, you may need to enable JavaScript!
  • TRPC6 in Human [GtoPdb: 491] [UniProtKB: Q9Y210]
There should be some charts here, you may need to enable JavaScript!
  • TRPC7 in Human [GtoPdb: 492] [UniProtKB: Q9HCX4]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TRPC3 in Human [GtoPdb: 488] [UniProtKB: Q13507]
GtoPdb Measuring inhibition of calcium flux in HEK293 cells expressing hTRPC3, in a FLIPR assay. - 6.08 pIC50 840 nM IC50 ChemMedChem (2018) 13: 1028-1035 [PMID:29522264]
TRPC6 in Human [GtoPdb: 491] [UniProtKB: Q9Y210]
GtoPdb Measuring inhibition of calcium flux in HEK293 cells expressing hTRPC6, in a FLIPR assay. - 7.2 pIC50 63 nM IC50 ChemMedChem (2018) 13: 1028-1035 [PMID:29522264]
TRPC7 in Human [GtoPdb: 492] [UniProtKB: Q9HCX4]
GtoPdb Measuring inhibition of calcium flux in HEK293 cells expressing hTRPC7, in a FLIPR assay. - 6.66 pIC50 220 nM IC50 ChemMedChem (2018) 13: 1028-1035 [PMID:29522264]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.