CRAC channel inhibitor 5b [PMID: 26256403]

Ligand id: 10042

Name: CRAC channel inhibitor 5b [PMID: 26256403]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 23.55
Molecular weight 330.15
XLogP 4.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(4-chlorophenyl)-1,3-dimethyl-3-[1-(4-methylphenyl)propyl]urea
Comments
CRAC channel inhibitor 5b is a selective ORAI1 inhibitor that was identified through SAR of CRAC channel inhibitor 1 [PMID: 26256403] [1].
Database Links
GtoPdb PubChem SID 375973230
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