Synonyms: compound 57 [PMID: 30106292]
Compound class:
Synthetic organic
Comment: LIT-927 is a small molecule that binds to and neutralises the chemokine CXCL12 [1]. It has been termed a 'neutraligand'. LIT-927 was developed as an alternative strategy to inhibitors for CXCL12's cognate receptors CXCR4 or CXCR7, as a potential anti-inflammatory agent.
|
|
Classification ![]() |
|
Compound class | Synthetic organic |
IUPAC Name ![]() |
4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one |
Synonyms ![]() |
compound 57 [PMID: 30106292] |
Database Links ![]() |
|
GtoPdb PubChem SID | 375973262 |
PubChem CID | 137287575 |
Search Google for chemical match using the InChIKey | BYYRNPIGDRRGLJ-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | BYYRNPIGDRRGLJ |
UniChem Compound Search for chemical match using the InChIKey | BYYRNPIGDRRGLJ-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | BYYRNPIGDRRGLJ-UHFFFAOYSA-N |
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.
✖
LIT-927 (links to external site)
Cat. No. HY-112709 |