AM10257

Ligand id: 10177

Name: AM10257

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 67.15
Molecular weight 421.27
XLogP 5.3
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(adamantan-1-yl)-1-(5-hydroxypentyl)-4-methyl-5-phenyl-1H-pyrazole-3-carboxamide
Synonyms
AM-10257
Comments
AM10257 is a high affinity antagonist/inverse agonist of the cannabinoid CB2 receptor [1]. Low efficacy CB1 agonism has also been detected.
Database Links
GtoPdb PubChem SID 381118887
Search Google for chemical match using the InChIKey FMJXYCCDMAGPLE-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FMJXYCCDMAGPLE
Search UniChem for chemical match using the InChIKey FMJXYCCDMAGPLE-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FMJXYCCDMAGPLE