DH376

Ligand id: 10244

Name: DH376

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 80.48
Molecular weight 542.21
XLogP 6.16
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
{2-[(2R,5R)-2-benzyl-5-(but-3-yn-1-yl)piperidine-1-carbonyl]-2H-1,2,3-triazol-4-yl}bis(4-fluorophenyl)methanol
Synonyms
DH-376 | inhibitor 38
Comments
DH376 is a diacylglycerol lipase inhibitor [2].
Database Links
BindingDB Ligand 50211257
ChEMBL Ligand CHEMBL3895863
GtoPdb PubChem SID 381744926
PubChem CID 129188688
Search Google for chemical match using the InChIKey GVLOFRPVRYAFKI-VSGBNLITSA-N
Search Google for chemicals with the same backbone GVLOFRPVRYAFKI
Search UniChem for chemical match using the InChIKey GVLOFRPVRYAFKI-VSGBNLITSA-N
Search UniChem for chemicals with the same backbone GVLOFRPVRYAFKI