M084   Click here for help

GtoPdb Ligand ID: 10288

Synonyms: M-084
Compound class: Synthetic organic
Comment: M084 is a potent inhibitor of TRPC4 and TRPC5, and a weak inhibitor of TRPC3 [2]. It is a good pharmaceutical tool for investigating the physiological and pathophysiological functions of TRPC4/C5 channels.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 40.71
Molecular weight 189.13
XLogP 2.81
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CCCCNc1nc2c([nH]1)cccc2
Isomeric SMILES CCCCNc1nc2c([nH]1)cccc2
InChI InChI=1S/C11H15N3/c1-2-3-8-12-11-13-9-6-4-5-7-10(9)14-11/h4-7H,2-3,8H2,1H3,(H2,12,13,14)
InChI Key OKKUCNXCFWODOE-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
N-butyl-1H-benzimidazol-2-amine
Synonyms Click here for help
M-084
Database Links Click here for help
CAS Registry No. 51314-51-3 (source: PubChem)
ChEMBL Ligand CHEMBL1376358
GtoPdb PubChem SID 381744969
PubChem CID 284016
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