AM12   Click here for help

GtoPdb Ligand ID: 10292

Synonyms: 3,5,7-trihydroxy-2-(2-bromophenyl)-4H-chromen-4-one | AM-12
Compound class: Synthetic organic
Comment: AM12 is a synthetic derivative of the naturally occurring flavonol galangin. Like galangin it inhibits TRPC5-mediated calcium entry in to cells [1].
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 0
Hydrogen bond donors 3
Rotatable bonds 1
Topological polar surface area 90.9
Molecular weight 347.96
XLogP 4.63
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES Oc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccccc1Br
Isomeric SMILES Oc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccccc1Br
InChI InChI=1S/C15H9BrO5/c16-9-4-2-1-3-8(9)15-14(20)13(19)12-10(18)5-7(17)6-11(12)21-15/h1-6,17-18,20H
InChI Key OVIAJBSVWWYJSD-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
2-(2-bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one
Synonyms Click here for help
3,5,7-trihydroxy-2-(2-bromophenyl)-4H-chromen-4-one | AM-12
Database Links Click here for help
GtoPdb PubChem SID 381744973
Search Google for chemical match using the InChIKey OVIAJBSVWWYJSD-UHFFFAOYSA-N
Search Google for chemicals with the same backbone OVIAJBSVWWYJSD
Search UniChem for chemical match using the InChIKey OVIAJBSVWWYJSD-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone OVIAJBSVWWYJSD

Product suppliers

View disclaimer

Tocris
AM 12
Cat. No. 6495