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Synonyms: FZD8-Fc | OMP-54F28 | OMP54F28
Compound class:
Peptide
Comment: Ipafricept (OMP-54F28) is a fusion protein that fuses the FZD8 cysteine-rich domain to human IGHG1 Fc fragment [1]. It acts as a soluble decoy receptor for WNT ligands, and exhibits antitumour efficacy in vivo. Produced by OncoMed Pharmaceuticals.
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Classification  |
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| Compound class | Peptide |
| International Nonproprietary Names |
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| INN number | INN |
| 9810 | ipafricept |
| Synonyms |
| FZD8-Fc | OMP-54F28 | OMP54F28 |
| Database Links |
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| Specialist databases | |
| IMGT/mAb-DB | 475 |
| Other databases | |
| GtoPdb PubChem SID | 381745006 |
| Search PubMed clinical trials | ipafricept |
| Search PubMed titles | ipafricept |
| Search PubMed titles/abstracts | ipafricept |
