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ipafricept   Click here for help

GtoPdb Ligand ID: 10325

Synonyms: FZD8-Fc | OMP-54F28 | OMP54F28
Compound class: Peptide
Comment: Ipafricept (OMP-54F28) is a fusion protein that fuses the FZD8 cysteine-rich domain to human IGHG1 Fc fragment [1]. It acts as a soluble decoy receptor for WNT ligands, and exhibits antitumour efficacy in vivo. Produced by OncoMed Pharmaceuticals.
Classification Click here for help
Compound class Peptide
International Nonproprietary Names Click here for help
INN number INN
9810 ipafricept
Synonyms Click here for help
FZD8-Fc | OMP-54F28 | OMP54F28
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 475
Other databases
GtoPdb PubChem SID 381745006
Search PubMed clinical trials ipafricept
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