verucerfont

Ligand id: 10378

Name: verucerfont

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 90.37
Molecular weight 406.21
XLogP 4.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
International Nonproprietary Names
INN number INN
9197 verucerfont
Synonyms
Compound (S)-8d [PMID: 21074436] | GSK-561679 | GSK561679 | NBI-77860 | NBI77860
Comments
Verucerfont (NBI-77860 or GSK561679) is an orally available, brain penetrant and selective corticotropin releasing factor-1 (CRF-1) receptor antagonist [2].
Database Links
BindingDB Ligand 50417503
DrugBank Ligand DB12512
GtoPdb PubChem SID 384403658
PubChem CID 11596613
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