HSD1590

Ligand id: 10424

Name: HSD1590

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 91.26
Molecular weight 359.14
XLogP 3.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Comments
HSD1590 is a boronic acid-containing Rho-associated kinase (ROCK) inhibitor [1]. In vitro, it is more potent than netarsudil at binding to or inhibiting ROCK enzymatic activities.
Database Links
GtoPdb PubChem SID 385612184
Search Google for chemical match using the InChIKey WTZMCUOBQPTERK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WTZMCUOBQPTERK
Search UniChem for chemical match using the InChIKey WTZMCUOBQPTERK-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WTZMCUOBQPTERK