Synonyms: BTRX335140 | compound 58 [PMID: 30707578] | CYM-53093 | CYM53093
Compound class:
Synthetic organic
Comment: BTRX-335140 (a.k.a. CYM-53093) is a selective κ opioid receptor antagonist [1]. It has favourable drug-like properties in preclinical models, and is being proposed as a potential therapeutic for migraine [2], stress-related mood disorders (including depression), anxiety, and drug abuse.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
1-[6-ethyl-8-fluoro-4-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-4-yl)piperidin-4-amine |
Synonyms ![]() |
BTRX335140 | compound 58 [PMID: 30707578] | CYM-53093 | CYM53093 |
Database Links ![]() |
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GtoPdb PubChem SID | 385612212 |
PubChem CID | 137434175 |
Search Google for chemical match using the InChIKey | CQOJHAJWCDJEAT-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | CQOJHAJWCDJEAT |
Search UniChem for chemical match using the InChIKey | CQOJHAJWCDJEAT-UHFFFAOYSA-N |
Search UniChem for chemicals with the same backbone | CQOJHAJWCDJEAT |