zagotenemab

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zagotenemab

GtoPdb Ligand ID: 10471

Synonyms: LY-3303560 | LY3303560

Compound class: Antibody

Comment: LY3303560 is a monoclonal antibody that selectively targets tau protein aggregates [1]. It is being developed by Eli Lilly for potential to treat Alzheimer's disease. The primary epitope for LY3303560 is located in the N-terminal region of tau.

Summary
Biological activity
Clinical data
References

References
1. Alam R, Driver D, Wu S, Lozano E, Key SL, Hole JT, Hayashi ML, Lu J. (2017) Preclinical characterization of an antibody [LY3303560] tyargeting aggregated Tau. Alzheimers Dement, 136 (7): P592–P593. DOI: 10.1016/j.jalz.2017.07.227

References

1. Alam R, Driver D, Wu S, Lozano E, Key SL, Hole JT, Hayashi ML, Lu J. (2017)
Preclinical characterization of an antibody [LY3303560] tyargeting aggregated Tau.
Alzheimers Dement, 136 (7): P592–P593. DOI: 10.1016/j.jalz.2017.07.227