bemcentinib

Ligand id: 10478

Name: bemcentinib

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 97.26
Molecular weight 506.29
XLogP 5.05
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
International Nonproprietary Names
INN number INN
10631 bemcentinib
Synonyms
BGB-324 | BGB324 | R-428 | R428
Comments
Bemcentinib (BGB324, R428) is a potent, selective and orally active AXL receptor tyrosine kinase inhibitor that was discovered by Rigel as R428 [1] and which is being developed by BergenBio for anti-cancer potential [2].
Database Links
BindingDB Ligand 50172079
CAS Registry No. 1037624-75-1 (source: WHO INN record)
ChEMBL Ligand CHEMBL3809489
GtoPdb PubChem SID 385612237
PubChem CID 46215462
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