Synonyms: compound 11a [PMID: 31811124] | ONO2570366
Compound class:
Synthetic organic
Comment: ONO-2570366 is an antagonist of the cysteinyl leukotriene receptors CysLT1 and CysLT2 [1]. It has been used to elucidate the three dimensional structure of the CysLT2 receptor and its ligand-selectivity determinants.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
(2S)-4-(3-carboxypropyl)-8-[[4-[4-(2-chloro-5-fluorophenyl)butoxy]benzoyl]amino]-2,3-dihydro-1,4-benzoxazine-2-carboxylic acid |
Synonyms |
compound 11a [PMID: 31811124] | ONO2570366 |
Database Links | |
Specialist databases | |
GPCRdb Ligand | ONO-2570366 |
Other databases | |
GtoPdb PubChem SID | 404859027 |
PubChem CID | 145704683 |
RCSB PDB Ligand | KNW |
Search Google for chemical match using the InChIKey | JCUVQOJHURMRKB-SANMLTNESA-N |
Search Google for chemicals with the same backbone | JCUVQOJHURMRKB |
UniChem Compound Search for chemical match using the InChIKey | JCUVQOJHURMRKB-SANMLTNESA-N |
UniChem Connectivity Search for chemical match using the InChIKey | JCUVQOJHURMRKB-SANMLTNESA-N |