PSB-1584   Click here for help

GtoPdb Ligand ID: 10717

Synonyms: 6-hexylaminouracil | compound 20 [PMID: 30023867] | PSB1584
Compound class: Synthetic organic
Comment: PSB-1584 is a non-biased, high affinity agonist of the Gi protein-coupled receptor GPR84 [2]. A radiolabelled version ([3H]PSB-1584; KD 2.08 nM) which effectively labels GPR84 in native cells and tissues has been synthesised [1].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 77.75
Molecular weight 211.13
XLogP 2.68
No. Lipinski's rules broken 0
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Canonical SMILES CCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Isomeric SMILES CCCCCCNc1cc(=O)[nH]c(=O)[nH]1
InChI InChI=1S/C10H17N3O2/c1-2-3-4-5-6-11-8-7-9(14)13-10(15)12-8/h7H,2-6H2,1H3,(H3,11,12,13,14,15)
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
Synonyms Click here for help
6-hexylaminouracil | compound 20 [PMID: 30023867] | PSB1584
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Specialist databases
GPCRdb Ligand PSB-1584
Other databases
BindingDB Ligand 50028344
ChEMBL Ligand CHEMBL124977
GtoPdb PubChem SID 405067311
PubChem CID 44349321
Search Google for chemical match using the InChIKey SDXQSUJXSHUIBQ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SDXQSUJXSHUIBQ
UniChem Compound Search for chemical match using the InChIKey SDXQSUJXSHUIBQ-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey SDXQSUJXSHUIBQ-UHFFFAOYSA-N