Synonyms: VNRX-5133 | VNRX5133
Compound class:
Synthetic organic
Comment: Taniborbactam (VNRX-5133) is a clinical stage, injectable, broad-spectrum β-lactamase inhibitor [1,3]. It has activity against both serine- and metallo-β-lactamases (e.g. oxacillinase, Klebsiella pneumoniae carbapenemase, New Delhi metallo-beta-lactamase, Verona integron-encoded metallo-beta-lactamase and extended spectrum beta-lactamase) [4]. Taniborbactam will be administered alongside the cephalosporin antibacterial cefepime. It is being developed by Venatorx Pharmaceuticals in partnership with the Global Antibiotic Research & Development Partnership (GARDP).
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
(3R)-3-[[2-[4-(2-aminoethylamino)cyclohexyl]acetyl]amino]-2-hydroxy-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid |
International Nonproprietary Names | |
INN number | INN |
10817 | taniborbactam |
Synonyms |
VNRX-5133 | VNRX5133 |
Database Links | |
Specialist databases | |
Antibiotic DB | VNRX-5133 (Taniborbactam) |
Other databases | |
CAS Registry No. | 1613267-49-4 (source: WHO INN record) |
GtoPdb PubChem SID | 405560215 |
PubChem CID | 76902493 |
RCSB PDB Ligand | KJK |
Search Google for chemical match using the InChIKey | PFZUWUXKQPRWAL-PXCJXSSVSA-N |
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UniChem Compound Search for chemical match using the InChIKey | PFZUWUXKQPRWAL-PXCJXSSVSA-N |
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