CGP7930   Click here for help

GtoPdb Ligand ID: 1079

Synonyms: CGP 7930 | CGP-7930
Compound class: Synthetic organic
Comment: CGP7930 was originally reported as a GABAB receptor positive allosteric modulator (PAM) [1,4], and it became a widely used pharmacological tool. PAM action at GABAA receptors and inwardly-rectifying potassium channel blockade (at higher concentrations) have subsequently been demonstrated [2]. These latter discoveries suggest that CGP7930 is unsuitable for use as a GABAB receptor-selective PAM.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 40.46
Molecular weight 292.24
XLogP 5.22
No. Lipinski's rules broken 1
Click here for help
Canonical SMILES OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C
Isomeric SMILES OCC(Cc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C)(C)C
InChI InChI=1S/C19H32O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,20-21H,11-12H2,1-8H3
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
Synonyms Click here for help
CGP 7930 | CGP-7930
Database Links Click here for help
Specialist databases
GPCRdb Ligand CGP7930
Other databases
CAS Registry No. 57717-80-3 (source: Scifinder)
ChEMBL Ligand CHEMBL1256697
GtoPdb PubChem SID 135650080
PubChem CID 5024764
Search Google for chemical match using the InChIKey XLWJPQQFJNGUPA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XLWJPQQFJNGUPA
UniChem Compound Search for chemical match using the InChIKey XLWJPQQFJNGUPA-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey XLWJPQQFJNGUPA-UHFFFAOYSA-N
Wikipedia CGP-7930

Product suppliers

View disclaimer

CGP 7930 (links to external site)
Cat. No. 1513