levofloxacin   Click here for help

GtoPdb Ligand ID: 10911

Synonyms: DR-3355 | Levaquin® | Quinsair®
Approved drug PDB Ligand
levofloxacin is an approved drug (FDA (1996), EMA (2015))
Compound class: Synthetic organic
Comment: Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 75.01
Molecular weight 361.14
XLogP 3.7
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CN1CCN(CC1)c1c(F)cc2c3c1OC[C@@H](n3cc(c2=O)C(=O)O)C
Isomeric SMILES CN1CCN(CC1)c1c(F)cc2c3c1OC[C@@H](n3cc(c2=O)C(=O)O)C
InChI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
InChI Key GSDSWSVVBLHKDQ-JTQLQIEISA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1996), EMA (2015))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
International Nonproprietary Names Click here for help
INN number INN
6708 levofloxacin
Synonyms Click here for help
DR-3355 | Levaquin® | Quinsair®
Database Links Click here for help
CAS Registry No. 100986-85-4 (source: PubChem)
ChEMBL Ligand CHEMBL33
DrugBank Ligand DB01137
DrugCentral Ligand 1569
GtoPdb PubChem SID 405560352
PubChem CID 149096
RCSB PDB Ligand LFX
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