Synonyms: CRS-3123 | REP-3123 | REP3123
Compound class:
Synthetic organic
Comment: CRS3123 is an orally bioactive, diaryldiamine compound that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria [1]. It has limited antibacterial activity against normal anaerobic gut flora (e.g. Clostridium ramosum, bifidobacteria, lactobacilli of the Lactobacillus casei-rhamnosus-plantarum group) and Gram-negative anaerobes.
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
5-[3-[[(4R)-6,8-dibromo-3,4-dihydro-2H-chromen-4-yl]amino]propylamino]-4H-thieno[3,2-b]pyridin-7-one |
Synonyms |
CRS-3123 | REP-3123 | REP3123 |
Database Links | |
Specialist databases | |
Antibiotic DB | CRS3123 (REP3123 ) |
Other databases | |
CAS Registry No. | 1013915-71-3 (source: ChemIDplus) |
ChEMBL Ligand | CHEMBL4297370 |
DrugBank Ligand | DB12262 |
GtoPdb PubChem SID | 405560432 |
PubChem CID | 16744283 |
RCSB PDB Ligand | U81 |
Search Google for chemical match using the InChIKey | NNTYBKTXMKBRFA-CQSZACIVSA-N |
Search Google for chemicals with the same backbone | NNTYBKTXMKBRFA |
UniChem Compound Search for chemical match using the InChIKey | NNTYBKTXMKBRFA-CQSZACIVSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | NNTYBKTXMKBRFA-CQSZACIVSA-N |