dapirolizumab pegol   Click here for help

GtoPdb Ligand ID: 11123

Synonyms: CDP-7657 | CDP7657 | DZP
Immunopharmacology Ligand
Compound class: Antibody
Comment: Dapirolizumab pegol (CDP7657) is a pegylated monovalent Fab' immunomodulator that targets CD40 ligand [1]. It was developed by UCB Pharma. Removal of the Fc domain prevented the increased risk of thrombotic events observed with an intact mAb.
Click here for help

Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

✖

View interactive charts of activity data across species
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9869 dapirolizumab pegol
Synonyms Click here for help
CDP-7657 | CDP7657 | DZP
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 481
Other databases
CAS Registry No. 1416147-64-2 (source: WHO INN record)
ChEMBL Ligand CHEMBL2109478
GtoPdb PubChem SID 434122183
Search PubMed clinical trials dapirolizumab pegol
Search PubMed titles dapirolizumab pegol
Search PubMed titles/abstracts dapirolizumab pegol