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Synonyms: anti-hC5aR-32F3A6 GL | IPH-5401 | NN-8210 | NNC-0215-0384
Compound class:
Antibody
Comment: Avdoralimab (IPH5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1, and blocks C5a/C5aR1 signalling in subsets of myeloid-derived suppressor cells (MDSCs) and neutrophils. It has immunomodulating activity.
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Classification  |
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| Compound class | Antibody |
| International Nonproprietary Names |
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| INN number | INN |
| 11081 | avdoralimab |
| Synonyms |
| anti-hC5aR-32F3A6 GL | IPH-5401 | NN-8210 | NNC-0215-0384 |
| Database Links |
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| Specialist databases | |
| IMGT/mAb-DB | 940 |
| Other databases | |
| GtoPdb PubChem SID | 440816714 |
| Search PubMed clinical trials | avdoralimab |
| Search PubMed titles | avdoralimab |
| Search PubMed titles/abstracts | avdoralimab |
