dotinurad   Click here for help

GtoPdb Ligand ID: 11389

Synonyms: FYU-981 | FYU981 | Urece®
Approved drug
dotinurad is an approved drug (Japan (2018))
Compound class: Synthetic organic
Comment: Dotinurad, a novel selective urate reabsorption inhibitor (SURI), that acts on the URAT-1 transporter.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 83.06
Molecular weight 356.96
XLogP 2.86
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES O=C(N1CS(=O)(=O)c2c1cccc2)c1cc(Cl)c(c(c1)Cl)O
Isomeric SMILES O=C(N1CS(=O)(=O)c2c1cccc2)c1cc(Cl)c(c(c1)Cl)O
InChI InChI=1S/C14H9Cl2NO4S/c15-9-5-8(6-10(16)13(9)18)14(19)17-7-22(20,21)12-4-2-1-3-11(12)17/h1-6,18H,7H2
InChI Key VOFLAIHEELWYGO-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (Japan (2018))
International Nonproprietary Names Click here for help
INN number INN
10438 dotinurad
Synonyms Click here for help
FYU-981 | FYU981 | Urece®
Database Links Click here for help
CAS Registry No. 1285572-51-1 (source: WHO INN record)
GtoPdb PubChem SID 440816758
PubChem CID 51349053
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