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epcoritamab   Click here for help

GtoPdb Ligand ID: 11442

Synonyms: epcoritamab-bysp | Epkinly® | GEN-3013 | GEN3013 | Tepkinly®
Approved drug Immunopharmacology Ligand
epcoritamab is an approved drug (FDA & EMA (2023))
Compound class: Antibody
Comment: Epcoritamab (GEN3013) is a novel CD3ε/CD20 bispecific IgG1 antibody that redirects CD3+ cytotoxic T cells to selectively destroy CD20+ve malignant B cells [1-2]. Its Fc domain has been mutated to prevent FcγR and complement binding.
Classification Click here for help
Compound class Antibody
Approved drug? Yes. EU EMA (2023)  |  US FDA (2023)
International Nonproprietary Names Click here for help
INN number INN
11078 epcoritamab
Synonyms Click here for help
epcoritamab-bysp | Epkinly® | GEN-3013 | GEN3013 | Tepkinly®
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 949
Other databases
GtoPdb PubChem SID 440816811
Search PubMed clinical trials epcoritamab
Search PubMed titles epcoritamab
Search PubMed titles/abstracts epcoritamab