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Synonyms: RC-18 | RC18 | Tai'ai®
telitacicept is an approved drug (China (2021))
Compound class:
Peptide
Comment: Telitacicept (RC18) is a recombinant fusion protein that combines the ligand-binding domain of the TACI receptor and the Fc component of human IgG. It was designed to inhibit the signalling of B cell BAFF (a.k.a. BLyS; TNFSF13B) and APRIL (TNFSF13) as a disease-modifying mechainism for the treatment of B cell-mediated autoimmune diseases [2-4,6].
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