Synonyms: MMV1582617 | NVP-INE963
Compound class:
Synthetic organic
Comment: INE963 is a potent antimalarial compound identified by the Novartis Institute for Tropical Diseases (NITD) during an optimization study of a series of 5-aryl-2-amino-imidazothiadiazole (ITD) derivatives [1]. The compound has progressed to clinical evaluation and was awarded MMV Project of the Year (2019).
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. |
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Classification ![]() |
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Compound class | Synthetic organic |
Ligand families/groups | Antimalarial ligands |
IUPAC Name ![]() |
4-(aminomethyl)-1-{5-[2-methoxy-6-(propan-2-yl)pyridin-3-yl]imidazo[2,1-b][1,3,4]thiadiazol-2-yl}piperidin-4-ol |
Synonyms ![]() |
MMV1582617 | NVP-INE963 |
Database Links ![]() |
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CAS Registry No. | 2640567-43-5 (source: Scifinder) |
GtoPdb PubChem SID | 461663484 |
PubChem CID | 156274257 |
Search Google for chemical match using the InChIKey | JYHSRMKXBAPFST-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | JYHSRMKXBAPFST |
UniChem Compound Search for chemical match using the InChIKey | JYHSRMKXBAPFST-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | JYHSRMKXBAPFST-UHFFFAOYSA-N |