Synonyms: drosophilin B | pleuromutilin
Compound class:
Natural product or derivative
Comment: Pleuromulin (also known as pleuromutilin) was initially isolated from fungal species of the genus Pleurotus and was the first pleuromutilin class antibacterial to be discovered [1]. Further optimization of pleuromulin led to the development of the clinically approved medicines lefamulin and retapamulin.
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Classification | |
Compound class | Natural product or derivative |
IUPAC Name |
[(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-hydroxyacetate |
International Nonproprietary Names | |
INN number | INN |
3933 | pleuromulin |
Synonyms |
drosophilin B | pleuromutilin |
Database Links | |
Specialist databases | |
Antibiotic DB | Pleuromutilin, drosophilin B |
Other databases | |
CAS Registry No. | 125-65-5 (source: Scifinder) |
ChEMBL Ligand | CHEMBL3989485 |
GtoPdb PubChem SID | 485206056 |
PubChem CID | 9886081 |
Search Google for chemical match using the InChIKey | ZRZNJUXESFHSIO-BKUNHTPHSA-N |
Search Google for chemicals with the same backbone | ZRZNJUXESFHSIO |
Search PubMed clinical trials | pleuromulin |
Search PubMed titles | pleuromulin |
Search PubMed titles/abstracts | pleuromulin |
UniChem Compound Search for chemical match using the InChIKey | ZRZNJUXESFHSIO-BKUNHTPHSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | ZRZNJUXESFHSIO-BKUNHTPHSA-N |