GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

cadonilimab   Click here for help

GtoPdb Ligand ID: 12966

Synonyms: AK-104 | AK104
Approved drug Immunopharmacology Ligand
cadonilimab is an approved drug (China NMPA (2022))
Compound class: Antibody
Comment: Cadonilimab (AK104) is a humanized, bispecific monoclonal antibody that simultaneously targets the immune checkpoint proteins PD-1 and CTLA-4. It was designed as a cancer immunotherapy (immuno-oncology) agent.
Click here for help

Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

✖

View interactive charts of activity data across species
Classification Click here for help
Compound class Antibody
Ligand families/groups Immune checkpoint modulators
Approved drug? Yes. China NMPA (2022)
International Nonproprietary Names Click here for help
INN number INN
11581 cadonilimab
Synonyms Click here for help
AK-104 | AK104
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1124
Other databases
GtoPdb PubChem SID 485206087
Search PubMed clinical trials cadonilimab
Search PubMed titles cadonilimab
Search PubMed titles/abstracts cadonilimab