tosatoxumab

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Ligands
tosatoxumab

GtoPdb Ligand ID: 13362

Synonyms: AR-301 | KBSA301 | Salvecin™

Comment: Tosatoxumab is a clinical stage fully human IgG1 monoclonal antibody that binds to Staphylococcus aureus alpha-toxin [1].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.

Summary
Biological activity
Clinical data
References

References
1. François B, Mercier E, Gonzalez C, Asehnoune K, Nseir S, Fiancette M, Desachy A, Plantefève G, Meziani F, de Lame PA et al.. (2018) Safety and tolerability of a single administration of AR-301, a human monoclonal antibody, in ICU patients with severe pneumonia caused by Staphylococcus aureus: first-in-human trial. Intensive Care Med, 44 (11): 1787-1796. [PMID:30343314]

References

1. François B, Mercier E, Gonzalez C, Asehnoune K, Nseir S, Fiancette M, Desachy A, Plantefève G, Meziani F, de Lame PA et al.. (2018)
Safety and tolerability of a single administration of AR-301, a human monoclonal antibody, in ICU patients with severe pneumonia caused by Staphylococcus aureus: first-in-human trial.
Intensive Care Med, 44 (11): 1787-1796. [PMID:30343314]