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Synonyms: AK-101 | AK101
ebdarokimab is an approved drug
Compound class:
Antibody
Comment: Ebdarokimab (AK101) is a humanized IgG1-κ, dual IL-12/IL-23 targeting monoclonal antibody. It binds to the common p40 subunit (IL12B) of these cytokines and disrupts pro-inflammatory signalling via their receptors on T cells and natural killer (NK) cells.
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| References |
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1. Jing R, Zhi X, Shao L. (2026)
Approvals by the China NMPA in 2025. Nat Rev Drug Discov, [Epub ahead of print]. [PMID:41688808] |
