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Synonyms: GMA-102
Compound class:
Antibody
Comment: Glutazumab (GMA102, Gmax Biopharm) is a monoclonal antibody fusion protein that behaves as a long-acting agonist at the glucagon like-peptide-1 (GLP-1) receptor [1]. It combines a humanized IgG2 monoclonal antibody against the GLP-1 receptor and a proteolysis-resistant derivative of human GLP-1 (7-35). Both the antibody component and GLP-1 ligand moiety of glutazumab are reported to contribute to the binding and activation of the receptor.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
