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raludotatug deruxtecan   Click here for help

GtoPdb Ligand ID: 14519

Synonyms: DS-6000 | DS-6000A | R-DXd
Compound class: Antibody
Comment: Raludotatug deruxtecan (R-DXd; DS-6000a) is an anti-CDH6 monoclonal conjugated to the chemotherapy agent deruxtecan (DXd; a derivative of the topoisomerase I inhibitor exatecan) [1-2]. The antitumour effect of raludotatug deruxtecan is due to intracellular release of the toxic payload; the naked antibody has no anti-tumour activity.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
12314 raludotatug deruxtecan
Synonyms Click here for help
DS-6000 | DS-6000A | R-DXd
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1350
Other databases
Search PubMed clinical trials raludotatug deruxtecan
Search PubMed titles raludotatug deruxtecan
Search PubMed titles/abstracts raludotatug deruxtecan