SRIF-28

Ligand id: 2020

Name: SRIF-28

Species: Human, Mouse, Rat

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View more information in the IUPHAR Pharmacology Education Project: srif-28

Structure and Physico-chemical Properties

2D Structure
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Synonyms
somatostatin 1-28 | SST-28
Comments
As with many peptide molecules there is some ambiguity in the literature as to the exact stereochemistry of SRIF-28. The structure shown here matches that shown in the PubChem entry linked to above, but the compound is also represented by CHEMBL442494 and CID 44388117.
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
SST somatostatin Human prepro-somatostatin SMST, somatostatin-14, somatostatin-28
Sst somatostatin Mouse prepro-somatostatin preprosomatostatin, Smst, SOM, SRIF
Sst somatostatin Rat prepro-somatostatin Smst, Somatostatin, SS-14, SS-28
Database Links
BindingDB Ligand 50254239
GtoPdb PubChem SID 135651887
PubChem CID 16133849
Search Google for chemical match using the InChIKey GGYTXJNZMFRSLX-DFTNLTQTSA-N
Search Google for chemicals with the same backbone GGYTXJNZMFRSLX
Search UniChem for chemical match using the InChIKey GGYTXJNZMFRSLX-DFTNLTQTSA-N
Search UniChem for chemicals with the same backbone GGYTXJNZMFRSLX
UniProtKB P60042 (Rn), P60041 (Mm), P61278 (Hs)

Product suppliers

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Tocris
Somatostatin 1-28
Cat. No. 1165