perphenazine   Click here for help

GtoPdb Ligand ID: 209

Synonyms: Decentan® | Fentazin® | Trilafon®
Approved drug
perphenazine is an approved drug (FDA (1957))
Compound class: Synthetic organic
Comment: Perphenazine is a typical antipsychotic drug, acting principally as a dopamine D2 receptor antagonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 55.25
Molecular weight 403.15
XLogP 3.86
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(Cl)cc2
Isomeric SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(Cl)cc2
InChI InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
InChI Key RGCVKNLCSQQDEP-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1957))
IUPAC Name Click here for help
2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
International Nonproprietary Names Click here for help
INN number INN
637 perphenazine
Synonyms Click here for help
Decentan® | Fentazin® | Trilafon®
Database Links Click here for help
BindingDB Ligand 50130273
CAS Registry No. 58-39-9
ChEBI CHEBI:8028
ChEMBL Ligand CHEMBL567
DrugBank Ligand DB00850
DrugCentral Ligand 2113
GtoPdb PubChem SID 135650810
PubChem CID 4748
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Wikipedia Perphenazine