TRAM-34   Click here for help

GtoPdb Ligand ID: 2336

Immunopharmacology Ligand
Compound class: Synthetic organic
Comment: TRAM-34 is a KCa3.1 channel blocker.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 17.82
Molecular weight 344.11
XLogP 6.47
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
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Canonical SMILES Clc1ccccc1C(n1cccn1)(c1ccccc1)c1ccccc1
Isomeric SMILES Clc1ccccc1C(n1cccn1)(c1ccccc1)c1ccccc1
InChI InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H
InChI Key KBFUQFVFYYBHBT-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
1-[(2-chlorophenyl)-di(phenyl)methyl]pyrazole
Database Links Click here for help
BindingDB Ligand 50279107
CAS Registry No. 289905-88-0 (source: Scifinder)
ChEMBL Ligand CHEMBL498270
GtoPdb PubChem SID 135651273
PubChem CID 656734
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Tocris
TRAM 34
Cat. No. 2946