colchicine

Ligand id: 2367

Name: colchicine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 83.09
Molecular weight 399.17
XLogP 2.96
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2009))
IUPAC Name
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]acetamide
Synonyms
Colcrys® | methoxylated analogue of XD1 | XD25
Comments
Colchicine is a microtubule inhibitor. It is a methoxylated analogue of XD1 (colchicein).
Database Links
BindingDB Ligand 50014846
BitterDB Ligand 92
CAS Registry No. 64-86-8 (source: DrugBank)
ChEBI CHEBI:27882
ChEMBL Ligand CHEMBL107
DrugBank Ligand DB01394
GtoPdb PubChem SID 135650118
PubChem CID 6167
RCSB PDB Ligand LOC
Search Google for chemical match using the InChIKey IAKHMKGGTNLKSZ-INIZCTEOSA-N
Search Google for chemicals with the same backbone IAKHMKGGTNLKSZ
Search UniChem for chemical match using the InChIKey IAKHMKGGTNLKSZ-INIZCTEOSA-N
Search UniChem for chemicals with the same backbone IAKHMKGGTNLKSZ
Wikipedia Colchicine