diazoxide   Click here for help

GtoPdb Ligand ID: 2409

Synonyms: Proglycem® | SCH-6783 | SRG-95213
Approved drug PDB Ligand
diazoxide is an approved drug (FDA (1973))
Compound class: Synthetic organic
Comment: Diazoxide is a potassium channel activator.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 66.91
Molecular weight 229.99
XLogP 1.94
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES Clc1ccc2c(c1)S(=O)(=O)N=C(N2)C
Isomeric SMILES Clc1ccc2c(c1)S(=O)(=O)N=C(N2)C
InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChI Key GDLBFKVLRPITMI-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1973))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name Click here for help
7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
International Nonproprietary Names Click here for help
INN number INN
1294 diazoxide
Synonyms Click here for help
Proglycem® | SCH-6783 | SRG-95213
Database Links Click here for help
BindingDB Ligand 50241108
CAS Registry No. 364-98-7
ChEBI CHEBI:4495
ChEMBL Ligand CHEMBL181
DrugBank Ligand DB01119
DrugCentral Ligand 854
GtoPdb PubChem SID 135650176
PubChem CID 3019
RCSB PDB Ligand 20J
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Wikipedia Diazoxide

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Tocris
Diazoxide
Cat. No. 0964