flecainide   Click here for help

GtoPdb Ligand ID: 2560

Synonyms: Tambocor®
Approved drug PDB Ligand
flecainide is an approved drug (FDA (1985))
Compound class: Synthetic organic
Comment: Flecainide is a class Ic antiarrhythmic agent.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 59.59
Molecular weight 414.14
XLogP 4.62
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES O=C(c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F)NCC1CCCCN1
Isomeric SMILES O=C(c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F)NCC1CCCCN1
InChI InChI=1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)
InChI Key DJBNUMBKLMJRSA-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1985))
IUPAC Name Click here for help
N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
International Nonproprietary Names Click here for help
INN number INN
4096 flecainide
Synonyms Click here for help
Tambocor®
Database Links Click here for help
BindingDB Ligand 50131434
CAS Registry No. 54143-55-4 (source: Scifinder)
ChEBI CHEBI:75984
ChEMBL Ligand CHEMBL652
DrugBank Ligand DB01195
DrugCentral Ligand 1176
GtoPdb PubChem SID 135650266
PubChem CID 3356
RCSB PDB Ligand K4D
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Wikipedia Flecainide