lidocaine   Click here for help

GtoPdb Ligand ID: 2623

Synonyms: Xylocaine®
Approved drug PDB Ligand
lidocaine is an approved drug (FDA (1948))
Compound class: Synthetic organic
Comment: Lidocaine was the first-in-class amino amide-type local anesthetic to be discovered.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 32.34
Molecular weight 234.17
XLogP 2.1
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CCN(CC(=O)Nc1c(C)cccc1C)CC
Isomeric SMILES CCN(CC(=O)Nc1c(C)cccc1C)CC
InChI InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
InChI Key NNJVILVZKWQKPM-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1948))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name Click here for help
2-diethylamino-N-(2,6-dimethylphenyl)acetamide
International Nonproprietary Names Click here for help
INN number INN
4202 lidocaine
Synonyms Click here for help
Xylocaine®
Database Links Click here for help
BindingDB Ligand 50017662
CAS Registry No. 137-58-6
ChEBI CHEBI:6456
ChEMBL Ligand CHEMBL79
DrugBank Ligand DB00281
DrugCentral Ligand 1579
GtoPdb PubChem SID 135650521
PubChem CID 3676
RCSB PDB Ligand LQZ
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Wikipedia Lidocaine

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Tocris
Lidocaine
Cat. No. 3057